Have you ever wondered how scientists know how a virus affects the human body? Or how they develop medicines and vaccines to reduce the impact of viruses like the one that causes COVID-19? The answer is organoids! These miniature models of human organs are grown in the laboratory. Scientists use organoids to determine how a virus attacks the body and identify possible treatments for the virus. We conducted a literature review of the organoids used in COVID-19 research. We found that COVID-19 research used many different types of organoids. We also learned how scientists created these organoids and what they taught us about the SARS-CoV-2 virus. We identified ways to improve this new method of disease research in the future.